nmr spectroscopy online course

Last Updated on August 8, 2022 by Team College Learners

In this course, you will learn how the interactions between protons in a molecule give rise to the pattern of signals in an NMR spectrum, and how these patterns can be used to determine the identity of molecules. The online spectroscopy courses will also cover the use of carbon-13 and fluorine-19 nuclear magnetic resonance spectroscopy in structure determination. With interactive elements, real NMR data sets, assessment questions and expert tutor support throughout, this online course provides a unique opportunity for you to expand your knowledge beyond the limits of your laboratory or literature research.

In this ir spectroscopy course you will learn the fundamentals of Spectroscopy and Magnetic Resonance Imaging which is used in medical diagnosis MRI. You will also learn how to acquire MRI images.

Molecules | Free Full-Text | Quantitative 1H-NMR Spectroscopy for Profiling  Primary Metabolites in Mulberry Leaves

List of online spectroscopy courses

This course will start with Basic principles of NMR, walk through the analysis of spectra and demonstrate the application of multidimensional NMR spectroscopy in Chemistry and structural Biology. 
INTENDED AUDIENCE: M. Sc./ PhD and Scientists working in Pharma and Biophrma IndustriesPREREQUISITES:          Under graduate level understanding of Physics and Mathematics
INDUSTRY SUPPORT : Biocon, Wockhardt, Aurobindo Biopharma etc

Course Status :Completed
Course Type :Elective
Duration :12 weeks
Start Date :29 Jul 2019
End Date :18 Oct 2019
Exam Date :16 Nov 2019 IST
Category :Chemistry
Credit Points :3
Level :Postgraduate

Course layout

Week 1 :

  • Nuclear Spin and Magnetic Moments 
  • Nuclear Spins in a Magnetic Field Spin 
  • Lattice Relaxation Spin temperature Resonance 
  • Absorption of Energy and The NMR Experiment Resonance 
  • Absorption of Energy and The NMR Experiment Kinetics of Resonance Absorption

Week 2 :

  • Selection Rules and Line widths 
  • Bloch equations
  • More about relaxation 
  • More about relaxation Sensitivity

Week 3 :

  • Instruction to operator Algebra 
  • Chemical Shift
  • Anisotropy of chemical shifts Learning spectral simulation 

Week 4 :

  • Factors Influencing Isotropic Chemical shifts: Spin Spin Coupling 
  • Analysis of NMR spectra of molecules 
  • Learning spectral simulation

Week 5 :

  • Dynamic Effects in the NMR spectra : Two site exchange
  • Collapse of spin multiplets
  • Conformational Averaging of J- values
  • Analysis of NMR spectra of molecules with J Values 

Week 6 :

  • Principles of Fourier transform
  • NMR Theorems on Fourier transforms
  • Practical aspects of recording FTNMR spectra
  • Free Induction Decay (FID) and the spectrum
  • Pulse repetition rate
  • Folding of signals
  • Acquisition time and the resolution
  • Data processing in FT
  • NMR Learning of Data processing 

Week 7 :

  • Dynamic range in FTNMR and solvent suppression
  • The Nuclear Overhauser Effect – Experimental Schemes,Advanced Treatment
  • Steady state NOE and Transient NOE 

Week 8 :

  • Spin Echo Uncoupled spins
  • Spin Echo Coupled spins
  • Spin-lattice relaxation
  • Spin-spin relaxation
  • Polarization transfer SPT and INEPT spectral simulation

Week 9 :

  • Density matrix, Elements of Density Matrix, Time evolution of density operator 
  • Time evolution of density operator 
  • Product operator formalism 

Week 10 :

  • Segmentation of the time axis
  • Two dimensional NMR 2D
  • Fourier Transformation in NMR
  • Peak shapes in 2D spectrum
  • Quadrature detection in two-dimensional NMR 

Week 11 :

  • 2D- resolution/ separation experiments
  • Two-dimensional correlation experiments COSY, TDQ-COSY etc TOCSY

Week 12 :

  • 2D NOESY, 2D ROESY, Heteronuclear COSY,
  • The HETCOR pulse sequence HSQC